NEW YORK (CNNfn) - NeoRx, a biotechnology company, saw its share price take off, after the company published a report that said a single dose of its Pretarget targeted radiation therapy cured lung, colon and breast cancers in laboratory mice.
Shares of Internet Capital Group, which invests in the business-to-business Internet market, jumped up 23 percent Monday, after its partner company announced an online automotive parts delivery venture.
On the downside, shares of Williams-Sonoma Inc., a kitchenware retailer, fell 41 percent, after the company said it expects disappointing earnings despite record sales for the year ended Jan. 30.
Monday's Winners
NeoRx Corp. (NERX: Research, Estimates) up 29-3/16 to 51.
Shares flew after the biotechnology company, NeoRx, published a report that said a single dose of its so-called Pretarget radiation therapy cured lung, colon and breast cancers in laboratory mice. The manuscript was published in the Feb. 15, 2000, issue of the Proceedings of the National Academy of Sciences.
PMC-Sierra Inc. (PMCS: Research, Estimates) up 35-1/2 to 236-1/2.
Credit Suisse First Boston analyst Charlie Glavin upped chipmaker PMC-Sierra's price target to 250. Goldman Sachs analyst Nathaniel Cohn also raised his 12-month price target on PMC-Sierra to $275 from $125.
Agilent Technologies Inc. (A: Research, Estimates) up 34-1/2 to 142-1/2.
Shares of Agilent Technologies Inc., a test and measurement equipment maker, surged after announcing a new telecommunications switching technology that speeds up fiber-optic networks. The company said that its new technology can route optical signals carrying voice, data or video without converting them from photons to electrons.
Yahoo! Inc. (YHOO: Research, Estimates) up 15-1/8 to 173-1/8.
Internet media group Yahoo! Inc. is scheduled to speak with analysts on Thursday.
Priceline.com Inc. (PCLN: Research, Estimates) up 10-1/4 to 85-1/4.
Priceline.com, an Internet retailer that lets shoppers bid on plane tickets, hotel rooms and other goods, will hold a conference with analysts Tuesday. The company may use the occasion to unveil a new alliance or product offering, which could help the money-losing company show a profit more quickly than some people expect, analysts said. Robertson Stephens reiterated its strong buy on the company.
Internet Capital Group (ICGE: Research, Estimates) up 24-15/16 to 144.
NetVendor, an Internet Capital Group partner company, and CAM International announced that the companies are partnering to deliver automotive parts via NetVendor's portal community AutopartsBIN.com.
Internet Capital Group invests in the business-to-business Internet market. NetVendor is a provider of electronic distribution channel solutions (e-Channels) for the automotive, electronics and industrial products markets. CAM International is an aftermarket auto parts redistributor.
Robertson Stephens also upgraded Internet Capital Group to "strong buy" from "buy" with a $250 price target.
Advanced Micro Devices (AMD: Research, Estimates) up 5-15/16 to 47-7/16.
The No. 2 computer chip maker Advanced Micro Devices unveiled the first 1 gigahertz (GHz) computer chip, beating its far larger competitor Intel Corp. to the punch, thus claiming industry bragging rights. The company said it had begun shipments of its 1 GHz AMD Athlon processors, an announcement that analysts had been anticipating this week. Intel also is expected to follow shortly with its own announcement, perhaps later this week.
Telemate.Net Software Inc. (TMNT: Research, Estimates) up 4-1/4 to 15.
Telemate.Net Software Inc., an Internet and network systems products provider, announced that it has entered into a reseller agreement with Cisco Systems. The Telemate.Net product line of comprehensive Internet usage management and reporting solutions has been added to the catalog of complimentary third-party product offerings that Cisco sells and supports.
Isis Pharmaceuticals (ISIP: Research, Estimates) up 8-1/8 to 32-1/2.
Isis Pharmaceuticals announced that it has received issuance of U.S. patents on inhibitors to 20 genes over the last two months. The patents cover the use of inhibitors against genes involved in several areas of disease, including inflammatory responses, drug resistance and cancer.
Loronix Information Systems Inc. (LORX: Research, Estimates) up 9-13/16 to 41-3/16.
Comverse Technology Inc., maker of software systems that allow more services over wireless communications devices, said it had agreed to buy Loronix Information Systems Inc., developer of digital video recording and management systems, in a stock deal worth about $225 million.
Mirage Resorts Inc. (MIR: Research, Estimates) up 2-3/4 to 18-5/8.
MGM Grand Inc., the casino operator controlled by billionaire Kirk Kerkorian, said it agreed to buy rival Mirage Resorts Inc. for a sweetened $21 a share, or about $4.4 billion in cash. MGM Grand also said it will assume about $2 billion in Mirage debt.
Monday's Losers
Williams-Sonoma Inc. (WSM: Research, Estimates) down 12-7/8 to 18.
Williams-Sonoma Inc., a specialty retailer of kitchenware, said it expects disappointing earnings of $1.15-$1.16 earnings per share despite record sales for the year ended Jan. 30. The company estimated fourth-quarter earnings per share of 81 to 82 cents, well below the 94-cent consensus estimate compiled by First Call/Thomson Financial.
Edison International (EIX: Research, Estimates) down 7-13/16 to 17-13/16.
Edison International announced that it is revising its 2000 earnings-per-share projection downward to a range of $1.90 to $2.10, from $2.20 to $2.30. This change is due to depressed revenue from Edison Mission Energy's (EME) plants at Fiddler's Ferry and Ferrybridge in the United Kingdom, brought on by a sharp drop in British electricity market prices and lower volume than anticipated. Merrill Lynch downgraded the company to "near-term neutral" from "near-term accumulation."
Bristol-Myers Squibb Co. (BMY: Research, Estimates) down 4-5/8 to 46-7/8.
Bristol-Myers Squibb Co. was downgraded by Salomon Smith Barney to "outperform" from "buy."
FLIR Systems Inc. (FLIR: Research, Estimates) down 8 to 9-1/8.
FLIR Systems Inc. said it had discovered accounting errors, and now expects fourth-quarter results to be materially below its previous forecasts. It said it may report a loss. A month ago, the maker of imaging devices projected fourth-quarter earnings per share would be up 8 to 12 percent from the year-earlier 53 cents. It forecast revenue of $57 million.
Before the February forecast, analysts had expected the company to earn around 87 cents a share for the fourth quarter. The consensus Wall Street estimate is now 58 cents a share, according to First Call/Thomson Financial. 
-- compiled by staff writer Lucy Banduci from wire reports
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