NEW YORK (CNN/Money) - U.S. stocks opened lower Tuesday after a long holiday weekend as oil prices spiked over $41 a barrel following a terrorist attack in Saudi Arabia that left 22 people dead.

After a few minutes of trading, all three major averages -- Dow Jones Industrial average (down 5.96 to 10182.49, Charts), the Nasdaq composite (down 4.31 to 1982.43, Charts) and the Standard & Poor's 500 (Charts) -- declined.

The attack in the Saudi city of Khobar rattled world oil markets and sent NYMEX July futures up $1.39 to trade at $41.27 a barrel. Before the attack, oil had fallen below $40 a barrel just ahead of the Memorial Day weekend, which kicked off the U.S. summer driving season.

Elsewhere, Mel Karmazin resigned Tuesday as president and chief operating officer of media conglomerate Viacom Corp. (VIA: unchanged at $37.27, Research, Estimates) The company also announced that Chairman and CEO Sumner Redstone, the company's largest shareholder, has indicated that he will relinquish his role as CEO within three years.

In the bond market, U.S. Treasurys fell, sending the yield on the 10-year note up to 4.66 percent from 4.60 late Friday.

In international trading, stocks finished mixed in Asia overnight and fell in midday trading in Europe.