NEW YORK (Fortune) -- We all know someone who's been there. You get the call for your dream gig, and you're so excited. Except for one small detail. It's in Omaha, or Tallahassee, or Albuquerque - a city you can barely find on a map.

Time was when this happened, you pulled out the old Yellow Pages and made the best of it. But one Web site, Reply! (http://www.reply.com/), is trying to make your life a little easier - at least when it comes to these key moments.

Billed as a way of "making life's big decisions easier," Reply! targets what CEO and founder Payam Zamani calls "life-stage events" - moving to a new city, buying and insuring a home or car, refinancing your home, purchasing life insurance and, in the near future, health and other arenas.

Consumers can register on Reply! at no charge, and the site hooks them up with professionals or service providers in the area or areas they request.

Moreover, once a customer registers and lists their prospective or current neighborhood, they also gain access to all sorts of data. This includes Reply!'s "Neighborhood Report," a detailed accounting of market-specific data, like recent home appreciation and school district ratings. And on Aug. 22, the company will be launching some new features, including an "aerial mapping home valuation tool," a map with data overlays that allows users to click on any of Reply!'s 70 million listed homes and find out its vital statistics.

For the couple moving from L.A. or New York to a small Midwestern town, it's the difference between making blind calls or having Reply! provide them with all the particulars about their new home and connect them with movers, local agents and even doctors who they can vet.

Those professionals - there are 15,000 real estate and automotive agents alone - pay Reply! a fee to be part of the service.

The consumer doesn't pay anyone - unless of course, they end up closing on a house or doing some other deal. Customers can also browse listings and images on the site, and if for instance, they have questions or want someone to actually go to a house they're interested in and find out more, the local agents can do that for them, too.

It may sound simple, but for the person moving from Portugal to Savannah, Georgia, it's a huge deal.

That's what Les Winberg did a few years ago. After actually making the move, he worked with a few real estate agents he found the traditional way - through ads they'd posted - but he couldn't quite find what he wanted. So he registered with Reply!, and, "before I knew it, [Savannah Re/Max agent] John Conner was knocking on my door."

Winberg is semi-retired and dabbles in real estate investing. He and Conner have worked together on purchasing three houses for Winberg, and putting one renovated home on the market. "Some people might say it's a computer and not a human, but you have to have an open mind about it," Winberg says. "The computer factor brings the human factor, and it speeds up the whole process a great deal. It's the best of both worlds, and a lot of people don't even know it's out there."

So next time you're at a life-stage event - and it drives you to consider ending your life - this is one new approach that might just keep you going.