Take the Powell/Hyde Street cable car ($5) for great views from Nob and Russian hills. Get off near Ghirardelli Square at Fisherman's Wharf to start a culinary tour of one of the world's great eating cities.
Walk to Oakville Grocery on Leavenworth for a taste of Napa Valley without the two-hour drive: fabulous wine, artisan bread, cheese, and charcuterie. From there, catch the F-Market streetcar to the Ferry Building, a massive indoor market packed with ethnic restaurants and gourmet food shops. (The popular farmers' market is on Tuesdays and Saturdays.) Finally, take the F-Market streetcar back to Fourth and Market. Walk half a block southeast to Beard Papa's, a Japanese sweets shop (Yerba Buena Lane off Mission Street between Third and Fourth). Stroll through nearby Yerba Buena Gardens and enjoy your dessert.