4. Merrill Lynch
Global 500 rank: 100
2007 loss ($ millions): $7,777
Ticker: MER
Wall Street brokerage Merrill Lynch's tab for the subprime mess totaled $23 billion in 2007, causing a $7.8 billion net loss for the year. Those losses led Stanley O'Neal to resign as CEO, and former NYSE Euronext CEO John Thain stepped into the top job in November.
The brokerage soon secured cash transfusions from international investment funds based in countries like Kuwait, Korea and Saudi Arabia, but still struggles. Writedowns continued into the first quarter of 2008, and shares have lost more than a third of their value since the start of the year.
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Last updated July 09 2008: 8:26 AM ET
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