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5. Oracle
Oracle
Fortune 500 rank: 113

The business software behemoth is enjoying the fruits of its aggressive acquisition strategy, including the 2008 purchase of BEA Systems. Oracle's profits spiked 29.2% to $5.5 billion on a 24.6% increase in sales to $22 billion.

NEXT: Intel
Last updated April 29 2009: 1:31 PM ET
2009 Fortune 500
Top 50
Top 50
Exxon Mobil pushes Wal-Mart aside to retake the No. 1 slot this year. Which other companies made the top 50 this year? More
They're hiring!
They're hiring!
As many big companies are announcing mass layoffs, these Fortune 100 employers have at least 150 openings each. More
The biggest losers
The biggest losers
Companies from AIG to United Airlines, from ConocoPhillips to Motorola lost billions of dollars last year. Who lost the most? More
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