Heather Bresch
Heather Bresch
Company: Mylan Inc.
Fortune 500 rank: 418
First year as CEO: 2012

This daughter of U.S. Senator (and former West Virginia Governor) Joe Manchin III overcame a 2008 scandal involving an MBA she earned improperly at West Virginia U. She rises to the top of generic drugmaker Mylan after 20 years in operations and strategy.

Last updated October 26 2011: 12:52 PM ET
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