(FORTUNE Magazine) – ''Running a company is not fun most of the time.'' -FRED JOSEPH, 48, newly named C.E.O. of Drexel Burnham Lambert. ''I feel like Custer, being shot at from all sides. Maybe it's because I'm flamboyant, maybe it's because I'm a Democrat, maybe it's because I was a bachelor for a long time, maybe it's because I'm Jewish . . . I have no idea.'' -MARVIN WARNER, 66, former owner of Ohio's failed Home State Savings, on being blamed for the bank's fatal ties with ESM Government Securities. ''I'm heartsick. I did the best I could and I hate to feel that I didn't measure up.'' -DAVID O'BRASKY, 50, publisher of Conde Nast's Vanity Fair magazine, on being asked to resign.