Chairman, CEO and Chief Creative Officer, OWN, Chairman, Harpo
2011 rank: 16
Winfrey remains one of media's most influential women, but she's lost her Midas touch: June newsstand sales of O, the Oprah Magazine fell 17.9%, and OWN, a joint venture between Harpo and Discovery Communications, is struggling. It canceled The Rosie Show in March after low ratings. She'll need to turn OWN around to move back up the list -- and show she can still spin gold.