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The country's most heavily populated megapolitan braces for another boom. Where will most of the development go? Up: Urban infill will outstrip suburban growth.
Key demographic shift: Native residents will leave for the Sun Belt, but the loss will be offset by newcomers from abroad.
New growth industries: New York City and Boston will be hotbeds of quantum computing and encryption.
Best businesses to start: For-profit colleges and professional schools located near major cities.
Best residential real estate bet: A $325,000 house in Lehigh Valley, Pa., and not just because it has some of the cheapest land in the region. The area is becoming a medical-devices, health-care and distribution hub.
Best commercial real estate bet: Ripping down old big-box malls and converting them into denser developments with offices, shops and condos.
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