| 5.30 Data as of May 17 |  +0.21 / +4.13%Today’s Change | 2.98 Today|||52-Week Range 7.44 | +0.76% Year-to-Date |
| Mutual fund holders | 8.58% |
| Other institutional | 7.92% |
| Individual stakeholders | 1.68% |
| 3/31/2013 | FIDELITY MANAGEMENT & RESEARCH C... Bought 447.5 Thousand shares of Synergy Pharmaceuticals I... |
| 3/31/2013 | DEUTSCHE BANK SECURITIES, INC. Bought 363.2 Thousand shares of Synergy Pharmaceuticals I... |
| 3/31/2013 | THE VANGUARD GROUP, INC. Bought 298.0 Thousand shares of Synergy Pharmaceuticals I... |
| Stockholder | Stake | Shares owned | Total value ($) | Shares bought / sold | Total change |
|---|---|---|---|---|---|
| The Vanguard Group, Inc. | 2.91% | 2,621,686 | 13,763,852 | +298,036 | +12.83% |
| Fidelity Management & Research Co... | 2.65% | 2,393,254 | 12,564,584 | +447,500 | +23.00% |
| Baker Bros. Advisors LLC | 1.82% | 1,638,871 | 8,604,073 | 0 | 0.00% |
| BlackRock Fund Advisors | 1.75% | 1,574,423 | 8,265,721 | +149,746 | +10.51% |
| Wall Street Associates LLC | 1.09% | 984,300 | 5,167,575 | +8,100 | +0.83% |
| SSgA Funds Management, Inc. | 0.70% | 632,762 | 3,322,001 | +10,600 | +1.70% |
| Northern Trust Investments, Inc. | 0.68% | 610,274 | 3,203,939 | +47,022 | +8.35% |
| Morgan Stanley Smith Barney LLC (... | 0.56% | 502,900 | 2,640,225 | +13,850 | +2.83% |
| Deutsche Bank Securities, Inc. | 0.42% | 377,325 | 1,980,956 | +363,221 | +2,575.30% |
| Bailard, Inc. | 0.33% | 300,000 | 1,575,000 | +40,000 | +15.38% |
| Mutual fund | Stake | Shares owned | Total value ($) | Shares bought / sold | Total change |
|---|---|---|---|---|---|
| Fidelity Select Biotechnology Por... | 1.64% | 1,481,266 | 7,776,647 | -12,900 | -0.86% |
| Fidelity Small Cap Growth Fund | 0.89% | 800,000 | 4,200,000 | 0 | 0.00% |
| Vanguard Small Cap Index Fund | 0.85% | 770,002 | 4,042,511 | +770,002 | -- |
| iShares Russell 2000 Index Fund | 0.71% | 644,345 | 3,382,811 | -24,760 | -3.70% |
| Vanguard Total Stock Market Index... | 0.67% | 606,975 | 3,186,619 | +606,975 | -- |
| Vanguard Small Cap Growth Index F... | 0.60% | 540,918 | 2,839,820 | +540,918 | -- |
| Vanguard Extended Market Index Fu... | 0.33% | 299,258 | 1,571,105 | 0 | 0.00% |
| iShares Russell 2000 Growth Index... | 0.32% | 284,994 | 1,496,219 | -20,296 | -6.65% |
| CREF Stock Account | 0.21% | 189,407 | 994,387 | 0 | 0.00% |
| TFS Market Neutral Fund | 0.20% | 177,279 | 930,715 | +38,163 | +27.43% |
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