Fortune 500: Stock watch

Stocks generally are getting socked this year, but investors are loving these 12 big companies, among them discount retailers and a food producer. Read on to see who's up the most on the Fortune 500, who's down the most and why the list is shrinking fast.

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Longs Drug Stores

Return: +51.9%

As CVS and Walgreen battled this summer over the right to buy Longs (CVS won, but the deal hasn't closed), the drugstore chain kept growing stronger. The bidding war paid off for the Walnut Creek, Calif.-based business, which was the only major drug store to post an increase in share prices last quarter.

By Mina Kimes, reporter

NEXT: Big Lots

Last updated October 13 2008: 4:43 PM ET

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Source: Sungard

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Fortune 500: Stock watch

Stocks generally are getting socked this year, but investors are loving these 12 big companies, among them discount retailers and a food producer. Read on to see who's up the most on the Fortune 500, who's down the most and why the list is shrinking fast.