Republican senators' latest attempt to repeal Obamacare could be the most far-reaching of GOP efforts this year.

Senators Lindsey Graham of South Carolina and Bill Cassidy of Louisiana released a revised version of a bill that would eliminate or overhaul major sections of the health reform law. It goes even farther in allowing states to craft their own health insurance regulations, and it provides several sweeteners for holdout senators, particularly Lisa Murkowski of Alaska.

Now, however, Republicans likely have only one week left to use their 2017 budget reconciliation bill as a way to dismantle Obamacare with a simple majority in the Senate. The Graham-Cassidy bill is the only repeal effort left on the table.

(This story has been updated with the latest revisions to the Graham-Cassidy repeal bill, as of September 25.)

The Congressional Budget Office is expected to release a preliminary score of the bill this week, but it's not expected to include details on the impact on insurance coverage and premiums.

Here's what's in the bill:

Repeal the individual and employer mandates: Obamacare levies penalties on most Americans who don't have health insurance and larger employers who don't provide affordable coverage for their workers. The bill would eliminate the penalty, retroactive to 2016.

Related: Millions could be left uninsured under Obamacare repeal bill

Repeals Obamacare subsidies and ends Medicaid expansion funding: The legislation would eliminate Obamacare subsidies that lower premiums, deductibles and co-pays in 2020. It would also jettison federal funding for Medicaid expansion, which 31 states use to provide coverage for residents with incomes up to about $16,000.

The legislation would turn the federal funding for Medicaid expansion and the subsidies into a block grant program. States would be given a lump sum of money and would have a lot of leeway over how to spend it.

For instance, they could help enrollees pay their premiums and out-of-pocket costs or set up high-risk or reinsurance pools to help protect insurers from costly enrollees and entice them to stay in the individual market. States could use a portion of the money to help those enrolled in Medicaid afford care.

Tonight on CNN: Senators debate the future of Obamacare

Graham and Cassidy say that this provision would return power to the states and allow them to create programs that fit their residents' needs. Also, it seeks to equalize Medicaid funding across the states by taking money from states that expanded Medicaid and giving it to those that didn't. The revised bill changes the formula so the shift isn't as drastic -- more than a dozen of the states that expanded Medicaid are run by Republican governors.

But Democrats and consumer advocates say that many states, particularly those that expanded Medicaid, would lose a lot of federal funding, making it harder for them to provide coverage or assistance to their residents. Also, they note, the block grant is only authorized through 2026, jeopardizing the continuation of funding after that.

Loosens Obamacare's regulations regarding pre-existing conditions and financial protections: The bill would also let states alter several key Obamacare protections for those with pre-existing conditions. While it would still require insurers to provide coverage to everyone, states could loosen a lot of other rules.

So younger, healthier folks could see their premiums go down, but those who need care and older Americans in their 50s and 60s could find themselves priced out of policies or only able to buy skimpy plans that don't cover all their needs.

The legislation would let states eliminate Obamacare's essential health benefits provision, which mandates insurers cover an array of services, including hospitalization, maternity care, prescription drugs, mental health and substance abuse services. This could lower premiums somewhat and give consumers a wider choice of plans. But it would also make it harder for people to buy comprehensive policies so those with pre-existing conditions may not be able to find coverage that meets their health care needs.

States could also change many of Obamacare's financial protections, including limiting how much people must pay out of pocket each year and how much of the tab insurers must pick up. That means that insurers could once again offer plans with deductibles of $10,000 or more for a single person. Republicans have long criticized Obamacare for having high deductibles, which this year cannot exceed $7,150.

Also, states could allow insurers to create multiple risk pools -- meaning those who are healthy could be assigned to one risk pool with lower premiums, while those who are not could be put into another with higher rates.

The new bill would also let states change the Obamacare requirement that insurers could not charge older Americans in their 50s and early 60s more than three times the rates of younger enrollees. Under the Affordable Care Act, younger consumers essentially subsidized the premiums of older ones. All the GOP repeal bills this year have loosened this provision, which has led the influential AARP to blast Republicans for levying an "age tax" on older Americans.

And under Obamacare, many preventative services -- including annual checkups, mammograms and colonoscopies -- were free. States could make changes to this provision, too.

Related: Republicans revise health care bill to try to switch key votes

Sweetens deal for Alaska: In an important nod to Murkowski, the revised bill says Native Americans and Alaska Natives enrolled in Medicaid expansion prior to 2020 could continue to be eligible after that point. The state's sizable native population and that group's unique health needs has been a serious concern for Murkowski.

Also, the state would receive a 25% boost in federal matching funds for Medicaid due to its defined high level of poverty.

And Alaska would be eligible for a $500 million pot of money for states that have been granted a certain type of federal waiver. It is one of the few states to meet this criteria.

Revamps funding for Medicaid overall: The legislation would send the states a fixed amount of money per Medicaid enrollee, known as a per-capita cap, starting in 2020.

States could also opt to receive federal Medicaid funding as a block grant for the non-disabled adults and children in their program. Under a block grant, states would get a fixed amount of federal funding each year, regardless of how many participants are in the program.

States, however, cannot opt to receive block grant funding for elderly and disabled participants.

Graham-Cassidy would also shrink the program even more over time by pegging the annual growth rate of funding for children and non-disabled adults to standard inflation after 2024, rather than the more generous medical inflation.

Either per-capita caps or block grants would limit federal responsibility, shifting that burden to the states. However, since states don't have the money to make up the difference, they would likely either reduce eligibility, curtail benefits or cut provider payments. The block grant would be more restrictive since the funding level would not adjust for increases in enrollment, which often happens in bad economic times.

Related: Trump says GOP's health bill protects pre-existing conditions. Here's the truth

Allows states to institute work requirements for Medicaid: States would now be able to require adult Medicaid recipients to work. The disabled, elderly and pregnant women would be exempt, however.

Permits everyone in the individual market to buy catastrophic plans: Obamacare only allows those under age 30 to buy catastrophic policies, which usually have higher deductibles and fewer benefits. This legislation would allow anyone to buy these plans starting in 2019.

Repeals a handful of taxes: The bill would repeal the tax on over-the-counter medicine, health savings accounts and medical devices, a levy unpopular on both sides of the aisle. But it keeps in place Obamacare's taxes on the wealthy, health insurers and others.

Defunds Planned Parenthood: In keeping with longstanding Republican beliefs, the legislation prohibits federal funding for Planned Parenthood. But the restriction is only for a year, beginning when the bill is enacted.

Increases maximum contributions to health savings accounts: Today, individuals can save up to $3,400 and families can save up to $6,750 a year tax-free in a health savings account. The bill would raise that limit to the annual out-of-pocket maximum for high-deductible plans. For 2018, that would be $6,650 for individuals and $13,300 for families.