![Safra Catz](https://i2.cdn.turner.com/money/galleries/2010/fortune/1009/gallery.most_powerful_women.fortune/images/safra_catz.jpg)
Age: 48
The arrival of former HP CEO Mark Hurd could mean power shifts at Oracle, but Catz retains CEO Larry Ellison's trust. She's key to Oracle's acquisition strategy, which shows no signs of slowing.
NEXT: Sherilyn McCoy
Last updated September 30 2010: 2:47 PM ET