Boston
Opened: November 2009
Rates: From $225; $450 for suites
Located in the historic Ames Building -- dating to 1880 and considered Boston's first skyscraper -- the Ames merges Old World charm with New World luxury, thanks to a renovation by Morgans Hotel Group. It has 95 minimalist-chic rooms and an entire apartment for longer-term stays or business meetings -- and its eponymous restaurant has become one of Boston's dynamic nighttime hot spots.
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Last updated November 08 2010: 7:04 AM ET