Lehman Brothers went bankrupt in September, dealing a big blow to Wall Street and investor confidence.
The loss of the biggest businesses - Lehman Brothers (No. 37) and Countrywide Financial (No. 104) - is still being felt in the housing and financial markets. When it comes to the Fortune 500, the bigger they come, the harder they fall.
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Last updated October 13 2008: 4:43 PM ET