Selling securities that have done well locks in your gains; selling losers lets you reduce your capital-gains tax bite. You can write off $3,000 a year in investment losses and carry over the excess into future years.
Cons: You'll owe capital-gains taxes of up to 15% on an appreciated investment you've held for more than a year; if you've held it less than a year, you'll owe ordinary income tax.
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Last updated August 22 2008: 12:36 PM ET