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Bubble Trouble? 5 pricey stocks

Talk of a stock market bubble is growing louder. These stocks are some of the priciest in the S&P 500.

Vertex Pharmaceuticals

most expensive stocks vertex pharmaceuticals
  • Forward P/E: 132.4
  • 2014 performance: 30%

If retailers sold stocks, Vertex Pharmaceuticals would not be found in Wal-Mart.

That's because the biotech company is the most expensive S&P 500 stock, excluding REITs and companies valued at less than $10 billion.

Vertex Pharmaceuticals (VRTX) is clearly a rising star in the biotech world that the Federal Reserve recently singled out for possibly being overvalued.

The drug maker skyrocketed 40% during a single day last month after revealing a positive study on an experimental cystic fibrosis drug that could sell for more than $150,000 a year.

That June surge leaves Vertex up 31% on the year, easily outperforming the broader markets after soaring 77% in 2013.

Yet Vertex is projected to suffer its third consecutive year of red ink, with analysts modeling a loss of nearly $700 million. Sales exploded in 2011 to $1.4 billion from just $143.4 million the year before, but then dropped in 2013 and are set to plunge more than 50% this year to $542 million.

Part of Vertex's climb has been fueled by speculation that larger cash-rich biotech companies like Gilead Sciences (GILD) could be on the prowl for a major acquisition.

  @MattEganCNN - Last updated July 22 2014 01:26 PM ET

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