That depends on a whole bunch of things, like when you start investing, what you decide to invest in, and when you decide to retire.
But as a general rule, financial planners advise that every year you should invest the maximum possible in any tax-advantaged retirement plan that you're eligible for. And if you're getting started with retirement investing on the late side, you may need to invest additional money, over and beyond the money in such plans, into regular (taxable) investment accounts.
For a better sense of how much you'll need to invest, go to our retirement planner calculator.