One of the best things going for Kansas City, Mo. is housing affordability, with the median home value coming in at just three times the median base salary.

Kansas City also got a fairly high score for hiring opportunity. Companies actively hiring include Sprint, Saint Luke's Health System and Missouri Bank, according to Glassdoor. Hallmark Cards, Inc. and employee-owned engineering firm Burns McDonnell also call K.C. home.

Among the positions currently in demand: Sales engineers, registered nurses and accountants.