Company: Guardian Life
Fortune 500 rank: 245
First year as CEO: 2011
Most Powerful Women rank: 47
Mulligan joined the insurer as executive vice president in 2008, then quickly got promoted twice before moving into the CEO spot in July, making her one of 15 women to lead a Fortune 500 company. The fourth-largest mutual life insurer in the U.S. manages $33 billion in assets.
NEXT: Debra Reed