NEW YORK (CNNMoney.com) -- President Bush, answering reporters during a press conference in Chicago Friday, called protectionism a "worrisome" trend and compared it to national isolationism.

Speaking about trade issue with China Mr. Bush chided critics who say the US can't effectively compete with China.

"'There are people who say, 'Well, we can't compete with China; let's throw up roadblocks. Let's protect ourselves, or 'We don't want foreigners coming to invest in our country.'"

"I think that would be a mistake. I think that's the early sign of protectionist sentiments which would mean our economy wouldn't grow," Mr. Bush said, noting its "corollary would be isolationism."

Bush rebuked those worried about what happens only domestically and gave the HIV/AIDS epidemic in Africa and the humanitarian crisis in Darfur as examples of foreign problems that affect the US.

"The truth of the matter is, all of these issues are our problem," Mr. Bush said. "And if we became isolationists we would not do our duty to protect the American people and, kind of, lay the foundations for a better world."

Bush answered reporters' questions about a variety of foreign policy and economic issues while speaking at the Museum of Science and Industry.

Regarding surging gas prices, Bush indicated his administration has encouraged the use of ethanol, offered incentives for buying hybrids but asked for patience from the public in the matter.

"It took us a while to get in a position where we're reliant upon sources of energy from outside our boundaries, and it's going to take us a while to become less dependent," said Mr. Bush. "It just takes a while. Things just don't happen instantly."

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