Although remembered as the first American mass-produced car designed with the aid of wind tunnel testing - and for the sales that disappointed its champion Walter Chrysler - the Airflow (there was also a Chrysler version) was also the car that changed the way cars were made.
By moving the engine and passengers forward, enclosing the trunk and improving ride, handling, and weight distribution, the Airflow influenced auto design worldwide. The body of the first Toyota was based on the DeSoto Airflow
Source: Walter P. Chrysler Museum; "Standard Catalog of Chrysler," edited by James T. Lenzke (Krause Publications)