Perhaps the best-known spa in the U.S., this flagship branch of Canyon Ranch set the standard for destination spas when it opened in 1979.
Signature Treatment: The Yamuna Body Roll is a variation of a deep-tissue massage, performed with rubber balls ranging from 4 to 10 inches in diameter (50 minutes, $110).
800/659-6921 or 520/749-9000; www.canyonranch.com