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21. Wells Fargo
Wells Fargo
Fortune 500 rank: 41
2008 revenue: $51.7 billion
2008 total shareholder return: 2.4%

Financial services company Wells Fargo has fared better than its peers and became the nation's fourth largest after buying troubled rival Wachovia last year. But the bank had to take $25 billion in government aid as major write-downs pushed net income down to $2.66 billion from $8.06 billion.

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Last updated April 20 2009: 1:34 PM ET
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