The M35 earned the highest score of any sedan in Consumer Reports' testing, according to the magazine.
"Well equipped and comfortable, it's just as capable on a twisty two-lane road as it is cruising down the highway."
Like the smaller G35 - also a Top Pick - it's available with either rear- or all-wheel-drive. The V8-power M45 costs about $55,000.
In the same class, the BMW 530i and Audi A6 are also worth considering, the magazine said.