Fortune 500 rank: 152
2010 profit: $1.9 billion
After a year in which profits dipped and revenues plateaued, the enterprise storage company grew on both fronts: profits inched as sales rose from $14 billion to $17 billion. Acquisitions like Isilon and Greenplum helped better position the company to tackle solutions for cloud computing and large data sets, or "big data."
NEXT: 14. Liberty Media
Last updated May 05 2011: 2:53 PM ET