Fortune 500 rank: 35
2010 profit: $14.0 billion
In many ways, 2010 belonged to Apple, which launched two products to great success: the iPhone 4 sold 1.7 million units during its first three days on shelves, and the iPad moved nearly 14.7 million units by the end of the year, beating even the most generous analyst estimates and the company's own always-conservative profit outlooks.
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Last updated May 05 2011: 2:53 PM ET