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Gilead Sciences

Gilead Sciences
Rank: 56   Ticker: GILD   Market value: $29 billion
WHY IT'S HOT: Gilead's success in the HIV market has rocketed the company into the No. 3 spot among biotechs. Gilead has launched five drugs in six years, including Atripla, a revolutionary combination pill that allows HIV patients to take three treatments at once.

CHALLENGES AND OPPORTUNITIES: HIV is a very narrow market, and it accounts for 70 percent of Gilead's $2 billion in sales. The company also receives royalties on Roche's sales of Tamiflu, which is being stockpiled as a treatment for bird flu. Much of those profits could evaporate if the threat of that disease fades. Gilead is testing Viread, currently used as an HIV treatment, to see whether it can help healthy people avoid contracting the disease. But the company needs to expand beyond that one market. With $2.5 billion in cash and marketable securities on the books, CEO John Martin has money to spend on acquisitions. Most recently, he paid $365 million in August for privately held Corus Pharma, which is developing an inhaled antibiotic used to treat lung infections in patients with cystic fibrosis. Analysts speculate a bigger deal may be near - perhaps one that takes Gilead into the highly lucrative cancer market.

STOCK OUTLOOK: Biotech is one of the few areas of the market where a P/E of 30 is considered cheap. But Gilead's relatively low multiple reflects the concern that investors have for the company's thin pipeline. Gilead's HIV franchise is indeed potent. But until Martin comes up with another growth driver, the stock is no bargain.

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Most stock quote data provided by BATS. Market indices are shown in real time, except for the DJIA, which is delayed by two minutes. All times are ET. Disclaimer. Morningstar: © 2018 Morningstar, Inc. All Rights Reserved. Factset: FactSet Research Systems Inc. 2018. All rights reserved. Chicago Mercantile Association: Certain market data is the property of Chicago Mercantile Exchange Inc. and its licensors. All rights reserved. Dow Jones: The Dow Jones branded indices are proprietary to and are calculated, distributed and marketed by DJI Opco, a subsidiary of S&P Dow Jones Indices LLC and have been licensed for use to S&P Opco, LLC and CNN. Standard & Poor's and S&P are registered trademarks of Standard & Poor's Financial Services LLC and Dow Jones is a registered trademark of Dow Jones Trademark Holdings LLC. All content of the Dow Jones branded indices © S&P Dow Jones Indices LLC 2018 and/or its affiliates.