Jobs lost: 17,000
% drop (1 year): 5%
Remaining employees*: 304,000
Fortune 500 rank: 10
Though layoffs seem to be commonplace at H-P -- the Silicon Valley stalwart has pared away more than 75,000 workers over the past 10 years as it has transformed its business to include laptops and servers -- it has also grown quickly through acquisitions, most notably of Compaq and EDS. The acquisition of Palm announced last month will add another 900 workers to the company's headcount.
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Last updated May 13 2010: 9:10 AM ET
* Full-time equivalent employees as of the end of 2009