15 companies that will change the world

These game-changing startups are likely to upend existing industries - and spawn new entrepreneurial opportunities.

MFG.com
CEO Free is excited about a patent MFG.com filed earlier this year for predicting the prices of manufactured parts.
MFG.com
CEO: Mitch Free
Disruption: An online exchange for the manufacturing industry
Disrupted: Manufacturers' reps, parts brokers, and trading houses

MFG.com is rapidly becoming the eBay of manufacturing. In the past 12 months, $2 billion worth of gears, molds and machined parts were sourced and traded on the site. To participate, sellers pay an annual fee of $6,000 on average, and buyers pay nothing. Buyers describe the part they want and submit digital renderings, and industrial suppliers bid for the business. The site is on track to make $25 million in revenue, and book its first profit, this year.

An eBay for manufacturers

Blinkx

Raydiance

Expensr

Zipcar

MFG.com

Virgin Charter

PatientsLikeMe

Bloom Energy

Vanu

Zink

A123 Systems

Renewable Energy Group

Desktop Factory

Cree

One laptop per child
The New Disruptors video series Editor-at-Large Erick Schonfeld discovers startups with the potential to overturn existing industries or open up entirely new markets. (more)
Tomorrow's light With companies developing innovative ways to fight global warming, Cree founder John Edmond describes how LED lights are poised to change the way we see things. (more) video