Our past NLT picks: Where are they now?

Looking back at Moller International, Organic Bouquet, and Xethanol. Plus: 15 other companies we've previously profiled as the Next Little Thing.

Biophan Technologies
Biophan Technologies
When Biophan first made FSB's Next Little Thing list in 2005, its mission was to develop MRI technology in imaging and safety. It has since changed direction: "Our real focus is the circulatory system now," says interim CEO John Lanzafame.

As part of that new strategy, Biophan obtained a minority equity position in MYOTECH, a company devoted to rejuvenating stopped hearts, in late 2005. Today, Biophan owns 68% of MYOTECH and has made the Myotech Circulation Support System (CSS) the center of its business. The MYO-VAD is a flexible polymer cup that fits around and pumps the heart and can be installed in a patient's chest in three minutes. Since the device doesn't come in contact with circulating blood it reduces the risk of blood clots.

This past summer Biophan sold the patents for its MRI safety technology to Medtronic, a medical technology company. However, it will continue to license MRI imaging technology to Boston Scientific, which will pay a royalty on all products it sells featuring Biophan technology - an agreement Lanzafame estimates has billion dollar potential once Boston Scientific begins shipping products.

Xethanol

Organic Bouquet

Ocean Power Technologies

On Demand Books

Moller International

Migo Software

HyperActive Technologies

Biophan Technologies

Spine Wave

Freedom-2

Parker Boston Group

AbTech

John Fluevog Shoes

Regeneration Technologies (RTI)

LipoSonix

O'Live Spas

True Jeans

Zaiger Genetics
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Most stock quote data provided by BATS. Market indices are shown in real time, except for the DJIA, which is delayed by two minutes. All times are ET. Disclaimer. Morningstar: © 2018 Morningstar, Inc. All Rights Reserved. Factset: FactSet Research Systems Inc. 2018. All rights reserved. Chicago Mercantile Association: Certain market data is the property of Chicago Mercantile Exchange Inc. and its licensors. All rights reserved. Dow Jones: The Dow Jones branded indices are proprietary to and are calculated, distributed and marketed by DJI Opco, a subsidiary of S&P Dow Jones Indices LLC and have been licensed for use to S&P Opco, LLC and CNN. Standard & Poor's and S&P are registered trademarks of Standard & Poor's Financial Services LLC and Dow Jones is a registered trademark of Dow Jones Trademark Holdings LLC. All content of the Dow Jones branded indices © S&P Dow Jones Indices LLC 2018 and/or its affiliates.