60 of 100
BACK NEXT
60. Pittsburgh
Population: 320,335
Pros: Top-ranked research universities, affordable homes
Cons: Sub-par public schools, urban ills like crime

Over the past decade, Pittsburgh has swapped its smoke-belching steel mills for greener ventures like biotech, electro-optics, and light industrial enterprises. Help for business development is plentiful. Investment organization Innovation Works, entrepreneurial infrastructure support group Idea Foundry, and the small business development center at the University of Pittsburgh are among the resources available to entrepreneurs. Pittsburgh offers startups an array of municipal loans, tax credits, and even a few actual outright grants, such as those administered by the "Kick Start Partnerships" program.

Opportunities exist in the data storage and financial industries, as well as in servicing the major universities in the city, like Carnegie-Mellon and the University of Pittsburgh's medical campus, a healthcare and cancer research institution. Urban amenities like first-rate museums and a lively music and arts scene are abundant - and if you like golf, championship fairways are just a fifteen minute drive from downtown. -Lisa Palmer

Interactive map: Pittsburgh
Homes for sale Find homes for sale in Pittsburgh


NEXT: 61. Northport, N.Y.

Last updated July 02 2008: 11:16 AM ET
More Galleries
7 lifehacks to eliminate your holiday hassle Whether curating the perfect gift or finding a pet-sitter, these startups offer time-saving services that might just seem like holiday magic. More
San Francisco: The best city to make things From electric motorcycles to death shrouds, San Francisco's manufacturing sector is booming. More
6 designers shaking up fashion These designers are changing the way we dress, accessorize and shop, from custom made-to-fit dresses to smart jewelry that's actually stylish. More

Special Offer

Most stock quote data provided by BATS. Market indices are shown in real time, except for the DJIA, which is delayed by two minutes. All times are ET. Disclaimer.

Morningstar: © 2014 Morningstar, Inc. All Rights Reserved.

Factset: FactSet Research Systems Inc. 2014. All rights reserved.

Chicago Mercantile Association: Certain market data is the property of Chicago Mercantile Exchange Inc. and its licensors. All rights reserved.

Dow Jones: The Dow Jones branded indices are proprietary to and are calculated, distributed and marketed by DJI Opco, a subsidiary of S&P Dow Jones Indices LLC and have been licensed for use to S&P Opco, LLC and CNN. Standard & Poor's and S&P are registered trademarks of Standard & Poor’s Financial Services LLC and Dow Jones is a registered trademark of Dow Jones Trademark Holdings LLC. All content of the Dow Jones branded indices © S&P Dow Jones Indices LLC 2014 and/or its affiliates.